It is a medieval church in which the Romanesque style blends with the Byzantine one, evident in the plan and in many decorations. It rises in a spectacular position at the top of the Guasco hill, already occupied by the Acropolis of the Greek-Doric city, from where it dominates the whole city of Ancona and its gulf. In May 1926, Pope Pius XI elevated it to the dignity of a minor basilica.